AUGUST 2009
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Free online calculators for radioactivity calculations, detecting outliers, t tests, ANOVA post tests, and more.

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GraphPad Software
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La Jolla, CA 92037
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Update for InStat available
GraphPad InStat is our simple statistics program for those who don't need the graphing or curve-fitting capabilities of Prism. InStat is so easy to learn that anyone can get started in just a few minutes. We've just released version 3.1 for both Windows and Mac, and it is a free update to everyone who owns InStat 3.0.

The biggest change with InStat 3.1 is that it can now handle larger data tables. The maximum number of rows has been increased tenfold to 10,000, and the maximum number of columns has been doubled to 52. The updated InStat is also more compatible with current versions of Windows and Mac OSX and their help engines. It also now displays a progress dialog for lengthy calculations, and gives you the chance to cancel when a complex calculation takes too long. If you are unfamiliar with InStat and would like to give the new version a test drive, try it out with this free 30-day demo.

More than you probably want to know about logarithmic axes
Graphs below show the same data, plotted on a standard axis (left) and a log axis (right).

Logarithmic axes are widely used by students and scientists, but are a frequent source of confusion, frustration, and tech support. Read this 13 page article that explains the advantages and disadvantages to plotting data on a logarithmic axis. It also distinguishes plotting on a logarithmic axis from plotting values transformed to logarithms and gives some hints on creating logarithmic axes with Prism.

More articles by Dr. Motulsky:

An in-depth guide to dose response curves
While overkill for most pharmacologists, this is a unique resource for people who need to deal with complex dose-response relationships, including allosteric interactions, synergy, multi-step binding, cubic binding models and much more. It deals only with systems at equilibrium, so does not cover kinetics. If you are curious, start with this chapter, which explains many variations on the Hill equation, and the many uses of the term "logistic". If you haven't heard of the Hill equation, this book is not for you!

Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects. by Neils Bindslev, Coaction Publishing ISBN: 978-91-977071-0-7. Freely available online or order the book.

Click on the graphs below to learn how to combine points with a shaded range, and how to create a grouped box and whiskers plot.

Use Prism's Graph Gallery to view and work with multiple graphs
You probably know that clicking on the Graphs heading in the Prism Navigator tree brings up a gallery of all the graphs in your file. Double click on one to go to it. But you may not know that Prism 5 lets you do much more within the gallery. Drag and drop graphs to rearrange them. Select any or all the graphs in a file, and print, export, or apply color schemes to them at the same time. Use Magic to format several graphs match an example. Learn more.

Get the most from Prism's powerful copy and paste options
It is common to use Excel to organize and manipulate data and then copy selected values from Excel and paste into Prism. We think this is a great way to work -- keep all your data organized in Excel and then graph and analyze what you want in Prism. You don't have to organize your data in Excel to match Prism's data tables. When you paste, Prism lets you transpose, filter, and rearrange your data. With Prism Windows you can also choose how to link between the Prism file and your Excel spreadsheet Learn more.