 | Approaches to comparing models |
| How the AICc computations work |
- * -
** Asterisks to denote significance
- A -
Advice: Choosing a multiple comparisons test
Advice: How to understand a model
AIC
Akaike information criterion
Allosteric EC50 shift equation
Allosteric modulator of radioligand binding, equation
Ambiguous nonlinear regression
Analysis checklist. Correlation
Analysis checklist: Bland-Altman results
Analysis checklist: Column statistics
Analysis checklist: Contingency tables
Analysis checklist: Deming regression
Analysis checklist: Friedman's test
Analysis checklist: Kruskal-Wallis test
Analysis checklist: Linear regression
Analysis checklist: Mann-Whitney test
Analysis checklist: Nonlinear regression, "Ambiguous"
Analysis checklist: Nonlinear regression, "Bad initial values"
Analysis checklist: Nonlinear regression, "Don't fit"
Analysis checklist: Nonlinear regression, "Hit constraint"
Analysis checklist: Nonlinear regression, "Impossible weights"
Analysis checklist: Nonlinear regression, "Interrupted"
Analysis checklist: Nonlinear regression, "Not converged"
Analysis checklist: Nonlinear regression, "Perfect fit"
Analysis checklist: Nonlinear regression, "Too few points"
Analysis checklist: Nonlinear regression, comparing models
Analysis checklist: Nonlinear regression, general
Analysis checklist: Nonlinear regression, interpolating
Analysis checklist: One-way ANOVA
Analysis checklist: Paired t test
Analysis checklist: Repeated measures two-way ANOVA
Analysis checklist: Repeated-measures one way ANOVA
Analysis checklist: ROC curves
Analysis checklist: Survival analysis
Analysis checklist: Two-way ANOVA
Analysis checklist: Unpaired t test
Analysis checklist: Wilcoxon matched pairs test
Analyzing data, analysis constants
Analyzing data, chaining analyses
Analyzing data, changing inputs and choices
Annotating graphs and layouts, highlighting
Annotating graphs and layouts, lines and boxes
Annotating graphs and layouts, text
ANOVA, one-way, interpreting results
ANOVA, repeated measures one-way
ANOVA, two-way repeated measures
Assigning graphs to a layout, in tour
Association binding experiments
Association kinetics (one ligand concentration) equation
Association kinetics (two ligand concentrations) equation
Association then dissociation, equation
Asterisks, to denote significance
Asymmetrical (five parameter) dose-response equation
Asymmetrical confidence intervals, nonlinear regression
Automatic linking and updating
- B -
Bar graphs, don't use log Y axis
Batch processing. Prism Magic.
Bayesian perspective on statistical significance
Bell-shaped dose-response equation
Bin width in frequency distributions
Biphasic dose-response equation
Bonferroni post tests, after two-way ANOVA
Bonferroni tests after one-way ANOVA
- C -
Changing decimal places on data table
Changing subcolumns on data table
Chi-square test or Fisher's test?
CI, assessing coverage with simulations
Compare tab, nonlinear regression
Comparing slopes and intercepts:
Compatibility between Prism and other programs
Compatibility between Prism versions
Competitive binding, one site equation
Competitive binding, one site, homologous
Competitive binding, one site, with ligand depletion
Competitive binding, two sites, equation
Competitive bindings, equation for kinetics
Competitive inhibition of enzyme
Complexity, of equations, defined
Confidence bands, computation of
Confidence interval of a proportion
Confidence interval of parameters of nonlinear regression
Confidence interval of proportion
Confidence intervals, assessing covering with simulations
Confidence intervals, one sided
Confidence intervals, principles
Constants, hooking analysis constants
Constrain tab, nonlinear regression
Constraints in nonlinear regression, default
Correlation vs. linear regression
Cumulative Gaussian axes, fitting straight lines on
Cumulative Gaussian distribution, equation
Cumulative Gaussian distribution, fitting
- D -
D'Agostino-Pearson normality test
D'Agostino-Pearson normality test of residuals.
Data analysis
Data set constant
Data tables - changing the format
Data tables - starting or duplicating
Data tables - Which one for a bar graph
Data tables, column formatting
Data, pasting from Excel (Mac)
Data, pasting from Excel (Windows)
Diagnostics tab, nonlinear regression
Directories of templates, methods and example files
Dissociation constant, ambiguity
Dissociation kinetics equation
Don't fit. Nonlinear regression
Dose-response, Five parameters
Dose-response, three parameters
Duplicating a graph, templates
- E -
ECanything. Fitting dose-response curves.
Embedding and linking, data objects
Equations, adding your own set
Error bars, on survival curves
Example, saving a graph as one
Exchanging X and Y values
Exponential association equation, one phase
Exponential association equation, two phases
Exponential decay equation, one phase
Exponential decay equation, three phases
Exponential decay equation, two phases
Exporting graph and layout, in tour
Extremely significant, defined
- F -
F test, to compare nonlinear fits, interpreting
Family-wise significance level
File locations, templates, methods, examples
Fisher's test or chi-square test?
Fitting straight lines to semi-log graphs:
Five parameter dose-response curve
Flipping - transposing - a data table
Flipping pages. Landscape vs. portrait
Folders of templates, methods and example files
Frequency distribution, how to
Front-to-back order of data sets
- G -
Gaddum/Schild EC50 shift equation
Gallery, view and choose sheets
Gallery, working with multiple sheets
Gaussian distribution, equation
Gaussian distribution, fitting to frequency distribution
Gaussian distribution, origin of
Gehan-Breslow-Wilcoxon test to compare survival curves
Geometric mean
Graphing hints: Contingency tables
Graphing hints: Survival curves
Graphing tips: Frequency distributions
Graphing tips: Linear regression
Graphing tips: Repeated measures two-way ANOVA
GraphPad radioactivity web calculator
Graphs, exporting to Word or PowerPoint
Grid lines, equally spaced on axis
Guilty or not guilty? Analogy to understand hypothesis testing.
- H -
Hill slope, in saturation binding
Hit constraint. Nonlinear regression.
Horizontal vs. vertical graphs
How to: Contingency table analysis
How to: Frequency distribution
How to: Linear regression interpolation
How to: Linear regression lines
How to: Repeated measures one-way ANOVA
How to: Two-way ANOVA. Repeated measures by column
How to: Two-way ANOVA. Repeated measures by row
How to: Unpaired t test from averaged data
How to: Unpaired t test from raw data
How to: Wilcoxon matched pairs test
- I -
IF() statement in segmental regression
Importing options, info & notes
Impossible weights. Nonlinear regression.
Individual replicates, plotting
Inhibition of enzymes by substrate
Initial rate, in enzyme kinetics
Insert and maintain link to data objects
Insert data only
Inserting pictures and objects
Intercept of linear regression
Interpreting results: Bland-Altman
Interpreting results: Chi-square
Interpreting results: Comparing >2 survival curves
Interpreting results: Comparing two survival curves
Interpreting results: Fisher's exact test
Interpreting results: Friedman test
Interpreting results: Kaplan-Meier curves
Interpreting results: Kruskal-Wallis test
Interpreting results: Mann-Whitney test
Interpreting results: Normality test
Interpreting results: One-sample t test
Interpreting results: One-way ANOVA
Interpreting results: Paired t
Interpreting results: Relative risk and odds ratio
Interpreting results: Repeated measures one-way ANOVA
Interpreting results: Repeated measures two-way ANOVA
Interpreting results: ROC curves
Interpreting results: Sensitivity and specificity
Interpreting results: Two-way ANOVA
Interpreting results: Unpaired t
Interpreting results: Wilcoxon signed rank test
Interrupted nonlinear regression
Intranet, launching Prism scripts
- J -
- K -
Kaplan-Meier curves, interpreting
Key concept - linking and embedding data
Key concepts: Contingency tables
Key concepts: Multiple comparison tests
Key concepts: Receiver-operator characteristic (ROC) curves
Kinetics of competitive binding, equation
Kinetics of radioligand binding
Kolmogorov-Smirnov normality test
Kolmogorov-Smirnov test of residuals
Kruskal-Wallis, interpreting results
- L -
Landscape vs. portrait. Graphs.
Landscape vs. portrait. Tables
Launching scripts from a web page
Launching scripts from outside of Prism
Launching scripts using MacScript, Automator, or AppleScript
Law of mass action
Linear regression vs. correlation
Linear regression, comparing slopes and intercepts
Linear regression, how it works
Linear regression, when to use nonlinear instead
Linear vs. nonlinear regression
Lines, fitting with nonlinear regression
Linking and embedding, data objects
Linking of data to results to graph
Log Gaussian distribution, equation
log((inhibitor) vs. normalized response equation
log(agonist) vs. normalized response equation
log(agonist) vs. normalized response, equation
log(agonist) vs. response -- Variable slope equation
log(agonist) vs. response equation
log(antagonist) vs. normalized response-- Variable slope equation
log(inhibitor) vs. response -- Variable slope equation
log(inhibitor) vs. response, equation
Lorentzian distribution, basis for robust regression
- M -
Mac differences, pasting Prism graphs
Mac vs. Windows, compatibility
Make one graph look like another
Mantel-Cox comparison of survival curves
Medians, does the Mann-Whitney test compare?
Microsoft Excel files, importing
Microsoft Excel, pasting data from (Mac)
Microsoft Excel, pasting data from (Windows)
Mixed-model inhibition of enzyme
Monte Carlo simulations with scripts
Morrison equation of enzyme inhibition
Multiple comparison test, choosing
Multiple comparison tests after two-way ANOVA
Multiple comparison tests, after two-way ANOVA
Multiple comparisons of survival curves
Multiple comparisons, after one-way ANOVA
- N -
Noncompetitive inhibition of enzyme
Nonlinear regression, how it works
Nonlinear regression, unequal weighting
Nonlinear regression, when to use for fitting a line
Nonlinear vs. linear regression
Nonparametric tests, why Prism doesn't choose automatically
Normality test, residuals of nonlinear regression
Normalizing. Does it make sense for dose-response data?
Not converged. Nonlinear regression.
Not guilty or guilty? Analogy to understand hypothesis testing.
- O -
Off rate of radioligand binding
On rates of radioligand binding
One phase exponential association equation
One phase exponential decay equation
One site -- Fit total and nonspecific binding, equation
One site -- Specific binding equation
One site -- Total binding equation
One site -- Total, accounting for ligand depletion equation
One site competition binding with ligand depletion
One site competition equation
One site competition homologous competition
One site with allosteric modulator equation
One-sample t test, interpreting
One-sided confidence intervals
One-way ANOVA, interpreting results
OpenOutput command
Operational model. Partial agonists experiments
Operational model. Receptor depletion experiments
Orientation of tables when printed
Outlier removal, nonlinear regression
Outlier removal, when to avoid
Outliers, danger of identifying manually
Outliers, testing with Grubbs' test
Outliers, what to do when you find one
Output tab, nonlinear regression
- P -
P value, common misinterpretation
P value, interpreting when large
P value, interpreting when small
Parallel regression lines, testing for.
Parameters dialog, returning to
Parameters: Area under the curve
Parameters: Contingency tables
Parameters: Frequency distribution
Parameters: Smooth, differentiate or integrate a curve
Parameters: Survival analysis
Parameters: t tests (and nonparametric tests)
Paste special options, info & notes
Paste special options, placement
Pasting data from Excel (Windows)
Perfect fit. Nonlinear regression.
Plateau followed by one phase decay, equation
Polynomial regression
Portrait vs. landscape. Graphs.
Portrait vs. landscape. Tables.
Post test after one-way ANOVA, choosing
Post tests, after comparing survival curves
Post tests, after one-way ANOVA
Post tests, after two-way ANOVA
PowerPoint. One-click export to.
Prediction bands, computation of
Printing. Landscape vs. portrait. Graphs.
Printing. Landscape vs. portrait. Tables.
Prism gallery, view and choose sheets
Prism Gallery, working with multiple sheets
Prism Magic. Make graphs consistent
Probability axes, fitting straight lines on
Problems with copying and pasting
Projects, merging and splitting
Proportion, confidence interval of
Proportional hazards regression
- Q -
Q, ROUT coefficient
- R -
Radioligand binding, ligand depletion
Radioligand binding, nonspecific binding
Range tab, nonlinear regression
Receiver-operator characteristic (ROC) curves
Repeated experiments, template
Repeated measures two-way ANOVA
Repeated measures vs. "randomized block"
Repeated measures, one-way ANOVA
Repeated-measures one-way ANOVA
Replicates, fitting with nonlinear regression
Replicates, plotting individual
Results: Wilcoxon matched pairs test
Retrospective case-control study
Robust nonlinear regression, choosing
Rotating graphs. Horizontal vs. vertical
Rotating -transposing - a data table
ROUT method of outlier detection
ROUT coefficient, Q
ROUT method of identifying outliers
Rules for initial values in nonlinear regression
Running scripts for a web page
Running scripts from outside of Prism
Running scripts using MacScript, Automator, or AppleScript
Runs test following linear regression
Runs test, nonlinear regression
- S -
Saving templates, methods, and examples files in a lab
Savitsky, method to smooth curves
Script, to assess coverage of confidence intervals
Scripts, adding to the list of samples
Scripts, launching from other programs
Scripts, running from web page
Scripts, running using MacScript, Automator, or AppleScript
Scripts, to simulate nonlinear regression
SD of residuals, from nonlinear regression
SD vs. SEM
SE of best-fit parameters of nonlinear regression
Segmental nonlinear regression
SEM vs. SD
SEM, computing
Semilog graphs, straight lines on
Sequential approach to P values
Shapiro-Wilk normality test
Shapiro-Wilk normality test of residuals
Sharing parameters in nonlinear regression
Sigmoidal substrate velocity plots
Simulating data with random error
Simulation, to demonstrate Gaussian distribution
Simulations. Used to assess coverage of confidence intervals
Slope, testing if is really zero
Spearman correlation coefficient
SSreg, from nonlinear regression
Standard deviation, confidence interval of
Standard deviation, interpreting
Steady state, in enzyme kinetics
Stevens' categories of variables
Strikethough over numbers -- outliers
Substrate inhibition of enzymes
Summary table, nonlinear regression
sy.x, from nonlinear regression
Symmetrical confidence intervals, nonlinear regression
- T -
t test, use logs to compare ratios
Text. Using Word to add formatted text.
Three parameter dose-response curve
Three phase exponential decay equation
Too few points. Nonlinear regression
Tour step 1 - start a new project
Tour step 10 - automatic linking and updating
Tour step 10 - notes, highlighting, shortcuts
Tour step 2 - enter or import data
Tour step 3 - automatic graphing
Tour step 4 - analyze your data
Tour step 5 - customize your graph
Tour step 6 - print or export graphs and layouts
Tour step 7 - repeating work by cloning
Tour step 8 - change one graph to look like another
Transforms for pharmacology and biochemistry
Transforms of best-fit values of parameters of nonlinear regreseson
Transposing data as you paste (Mac)
Transposing data as you paste (Windows)
Two phase exponential association equation
Two phase exponential decay equation
Two site competition equation
Two sites -- Fit total and nonspecific binding, equation
Two sites -- Specific binding only, equation
Two-way ANOVA
Two-way ANOVA, repeated measures
- U -
Uncompetitive inhibition of enzyme
- V -
Variable slope vs. fixed slope, dose-response
Vertical text, problem with Mac
Vertical vs. horizontal graphs
- W -
Weighting, nonlinear regression
Weights tab, nonlinear regression
Wilcoxon (used to compare survival curves)
Wilcoxon signed rank test, choosing
Wilcoxon signed rank test, Interpreting results
Windows vs. Mac, compatibility
Word, using to add formatted text
Working with multiple projects
- X -
- Y -
- Z -
Zooming