GraphPad Curve Fitting Guide

Fitting a curve without a model

Fitting a curve without a model

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Fitting a curve without a model

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In some circumstances, your goal is simple. You don't care about models, and don't expect best-fit values that you can interpret. Instead, you just want to draw a smooth curve to make a graph look attractive, or to use as a standard curve.

Spline and Lowess curves

Using nonlinear regression with an empirical model