Prism Updates

The latest Prism version is 8.3.0 (Windows and Mac).

How to Update to Prism 8


Update for free by downloading the Prism 8 installer for your system (instructions):

Windows 64-bit | Windows 32-bit | Mac

Perpetual Customers

Contact us at to learn about upgrade options.

Latest Prism Releases

Prism 8.3.0

October 29, 2019

Introducing Logistic Regression: model binary probability (e.g. yes/no, pass/fail) with a single or multiple explanatory variables. Included in this release:

  • New simple logistic regression analysis in XY data tables
  • New multiple logistic regression analysis in Multiple Variables data tables
  • Improved support for macOS Catalina
  • Added analytical representations of polynomial functions (5th, 6th, and 10th order)
  • Improved auto-recovery of Prism files under specific situations
  • And many additional performance improvements and bug fixes

See full list

Prism 8.2.1

August 28, 2019

This release fixes multiple issues in Prism 8.2.0, and improves stability. See full list

Prism 8.2.0

July 22, 2019

Introducing new features, performance improvements and bug fixes for Prism 8, including:

  • New options for visualizing scatter plots. Choose from three different styles and set your preferred style as a default
  • New equations in the nonlinear regression equation library: Absolute IC50 and all dose-response equations with X as concentration OR log(concentration)
  • The option to set a graph's axis scale to a Natural Log (Ln) scale
  • The ability to add multiple annotations for a single bar (above, within at top, AND within at bottom)
  • The option to toggle between a "Data with Results" view in the Navigator (data tables and linked results sheets grouped), or separate "Data" and "Results" sections
  • Improved Results Tabs appearance, increasing visibility and usability
  • Expanded results from ordinary Two-way ANOVA, now including a "Data summary" section displaying a number of columns, rows, and values
  • Corrected results for repeated measures Two-way ANOVA when no variation between subjects exists
  • The ability to export semi-transparent objects on a graph to PDF

See full list

Also, introducing Prism Labs with the first release from our experimental workshop: explore how Prism can now identify "unstable" parameters in nonlinear regression instead of classifying entire model fits as "ambiguous". Learn more

Prism 8.1.2

May 28, 2019

This release fixes multiple issues in Prism 8.1.1, including fixing 'multiple comparisons' results in Two-way ANOVA when entering data as SD/SEM/CV and N. See full list

Prism 8.1.1

April 25, 2019

This release fixes multiple issues in Prism 8.1.0, including fixing 'multiple comparisons' results when comparing cell means in Two-way ordinary balanced ANOVA. See full list

Prism 8.1.0

April 3, 2019

Introducing new features, performance improvements and bug fixes for Prism 8, including:

  • New (and useful!) color schemes, including a color-blind safe palette. Learn more ›
  • Automatic color selection for annotations and labels for better contrast in graphs.
  • Correlation matrix analysis now generates a heatmap of R2 values.
  • Option to calculate profile likelihood CIs with ambiguous fits.
  • "Dunnett T3" test to compare the mean of each column with the mean of every other column after nonparametric one-way ANOVA.
  • Improved scatterplot appearance.

See full list

Prism 8.0.2

February 6, 2019

This release includes over 80 bug fixes for Prism 8, including performance and stability improvements. See full list

Prism 8.0.1

December 5, 2018

This release includes over 50 bug fixes for Prism 8, including performance and stability improvements. See full list

Prism 8.0.0

October 16, 2018

Prism 8 introduces brand new ways to organize, analyze, and graph your data, all while making the process easier and more intuitive. Powerful new analyses and graph styles provide more ways than ever to process and present your data, while familiar features have received comprehensive improvements to enhance and streamline your work. Despite all the changes, Prism is still Prism so you can be productive right away.


  • Mixed effects model for analysis of repeated measures ANOVA with missing data.
  • Multiple Variables Data Table for Multiple Linear Regression Analysis.
  • Nested Data Table for Nested t test and Nested One-way ANOVA (Mixed Effects Model).
  • Violin Plots for data distribution visualization.
  • Grouped graphs that show both bars and individual points.
  • Draw lines or brackets with centered text. Ideal for placing significance asterisks.
  • More normality tests and plotting.
  • More comprehensive options for one-, two- and three-way ANOVA.
  • Graph customization and annotation options
  • And much more!

Browse the User Guide »

Release notes

Prism 7.05/e

August 27, 2018

  • Improved the algorithm used by the Dunnett test when the sample sizes are unequal.
  • Fixed bug in some results of the test for linear trend following repeated measures one-way ANOVA.
  • Improved auto-recovering feature so that Prism does not crash when opening slightly damaged Prism files.
  • Update notifications to stay up-to-date.
  • Support for seamless subscription renewals without requiring reactivation.
  • And many other bugs fixes.

Release notes: Windows, Mac