GraphPad Statistics Guide

Newman-Keuls method

Newman-Keuls method

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Newman-Keuls method

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Prism offers the Newman-Keuls test (sometimes called the Student-Newman-Keuls test) for historical reasons, but we don't recommend ever using it.

This test is a powerful way to compare all pairs of means, reporting statistical significance but not confidence intervals or multiplicity adjusted P values. The problem is it is too powerful, and so it does not maintain the family-wise error rate at the specified level(2). In some cases, the chance of a Type I error can be greater than the alpha level you specified.  

1.MA Seaman, JR Levin and RC Serlin, Psychological Bulletin 110:577-586, 1991.