Exporting images to submit to Cadmus, a company that handles publication for many journals.

Cadmus Journal Service is the service provider for publishers of many scientific journals. Unfortunately, they are behind in updating their guidlines for digital art submission. (They still have only guides for Prism 3.)  

Cadmus provides a java-based tool called Rapid Inspector for you to pre-test your image files. As each journal may have unique requirements,  get the version of Rapid Inspector that has been customized for the journal you are submitting to. You can usually find a link in the Author's Instructions section of the journal submission website. That page should also explain what file formats the journal prefers.

Most journals now prefer EPS files (encapsulated postscript). These are more compact and sharper than TIFF files. Even if the journal you are submitting to doesn't list EPS as an acceptable format, ask them, since their printed guidelines may be out of date. We'd always suggest submitting EPS files first. Prism offers several choices when exporting to EPS format. When submitting EPS files to Cadmus:

• Choose the option not to include fonts. This format is a bit more compatible with other programs, but the computer that the file is opened on must have the same fonts installed for the image to look right. This article explains this option. This is only a choice with Prism Windows. The Mac version does not offer the option of including fonts, so its files are fine with Cadmus.
• Prism lets you create gray scale EPS files, or to encode color using either RGB or CMYK formats. Follow your journal's guidelines.

Once you've exported an EPS file from Prism, you'll probably want to see it to make sure it is correct. With Macs, this is no problem. Just double-click on the file and it will be opened in Preview, a program that is part of the OSX system (actually, Preview will convert from EPS to PDF, and display that). Windows, however, has no built-in program that can view EPS files. You'll have to find another program. Try double-clicking on the file to see if you already have a program that can open EPS files. If not, you'll have to find one. The free program GhostScript works well. 

If your journal rejects EPS files, the next choice should be TIFF. Depending on your journal's requirements, here are the best formats to submit:

 -TIFF Monochrome in 1200dpi

-TIFF RGB millions colors (for Prism 5 Mac, see this note.).

Note that Cadmus rejects these TIFF formats:  TIFF RGB 256 colors, TIFF CMYK, and TIFF Monochrome in 300 DPI . When it rejects RGB-256, the error message says "csIndex RGB color is not supported."

When choosing the number of dots per inch (dpi) note the difference between the size of the graph in Prism and the size it will be when published. If it will be published with a width of 2 inches, but in Prism it has a width of 6 inches and you export at that size, then the effective dpi on the printed page will be three (6/2) times higher than the dpi you choose in Prism.

If you are having trouble with older versions of Prism, upgrade to the latest version (or try the demo). Prism 6 does a better job of exporting to Cadmus than did Prism 5.