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The IC50. In many experiments, you vary the concentration of an inhibitor. With more inhibitor, the response decreases, so the dose-response curve goes ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

This model fits the two IC50 values of the unlabelled ligand. It does not report the two Ki values. The Ki values depend on the IC50s, the concentration of ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

IC50 is the concentration of agonist that gives a response half way between ... Depending on which units Y is expressed in, and the values of Bottom and Top, the ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Relative vs absolute IC50; Fitting the absolute IC50; Incomplete dose-respone curves; Troubleshooting fits of dose-response curves. Dose-response - Stimulation ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

IC50 is the concentration of agonist that gives a response half way between ... Depending on which units Y is expressed in, and the values of Bottom and Top, the ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Any attempt to determine an IC50 by fitting a curve to the data in the graph above will be useless. Prism might, or might not, be able to fit a ...

https://www.graphpad.com/guides/prism/7/curve-fitting/

IC50 (inhibitory concentration) is the concentration of a drug that elicits ... In ideal cases, the dose-response curve extends between the control values, and ...

GraphPad FAQs

... IC50 IC60 IC70 IC75 IC80 IC90 ED10 ED20 ED25 ED30 ED40 ED50 ED60 ED70 ED75 ED80 ED90 LD10 LD20 LD25 LD30 LD40 LD50 LD60 LD70 LD75 LD80 LD90. Explore the ...

GraphPad FAQs

Instead you enter the concentration of radioligand and its Kd as constants, and Prism directly fits the Ki of your cold compound. If you want to know the IC50, ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Fit the ratio of two IC50 values directly. From the results in step 8, you can compute what you want to know -- the ratio of the two EC50 values. But Prism ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/