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Equation: EC50 shift; Equation: Allosteric EC50 shift; Equation: ECanything; Equation: Absolute IC50. Receptor binding - Key concepts; Receptor binding ...

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The EC50 is determined by two properties of the agonist: •How well it binds to the receptor, quantified by the affinity of the drug for binding to its ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

LogEC50 is the logarithm of the EC50 (effective concentration, 50%). With different kinds of variables, this variable is sometimes called ED50 (effective ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Prism labels the fit 'ambiguous'. Instead of reporting the confidence interval of some parameters, it simply reports "very wide". The best-fit value of the EC50 ...

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The EC50; Confidence intervals of the EC50; Hill slope; Choosing a dose-response equation; Pros and cons of normalizing the data; The term "logistic"; 50% of ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

You have a choice, in the Confidence tab, to either mark selected parameters as "unstable", to mark entire fits as "ambiguous", or neither.

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Many log(dose) response curves follow the familiar symmetrical sigmoidal shape. The usual goal is to determine the EC50 of the agonist - the concentration that ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Equation: EC50 shift; Equation: Allosteric EC50 shift; Equation: ECanything; Equation: Absolute IC50. Receptor binding - Key concepts; Receptor binding ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Equation: EC50 shift; Equation: Allosteric EC50 shift; Equation: ECanything; Equation: Absolute IC50. Dose-response -- Special (X is Log[Concentration]) ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

The standard log(dose) vs. response curve is defined by the bottom, top, EC50, and slope. In this curve, the top and bottom parts are mirror images of each ...

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