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If you are thinking about two drugs working on different sites on the same receptor, read up on allosteric interactions. This is a special case of drug synergy ...

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Prism computes the values internally, but it doesn't show them to you. If you want to see the SD or SEM values: Go to the data table. Click analyze.

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Choose an equation where X is expected to be dose or concentration, and Prism will fit the EC50 or IC50 directly, with standard errors.

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Equation: Absolute IC50. Receptor binding - Key concepts; Receptor binding - Saturation binding; Receptor binding - Competitive binding; Receptor binding ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

With different kinds of variables, this variable is sometimes called ED50 (effective dose, 50%), or IC50 (inhibitory concentration, 50%, used when the curve ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Equation: Absolute IC50. Dose-response -- Special (X is Log[Concentration]); Receptor binding - Key concepts; Receptor binding - Saturation binding; Receptor ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Prism reports that the upper confidence limit is infinity when the model and data simply don't define the upper confidence limit.

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... IC50). Compare Across Single or Multiple Groups. Prism's Grouped and Column Graphs simplify flow cytometry analysis, guiding you to identify trends and ...

https://www.graphpad.com/features/

You need to decide when those likelihood are far enough apart that you will believe the parameters are different. Keywords: EC50 IC50 ED50 logIC50 logED50 log ...

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After fitting the log of the EC50, Prism does the antilogarithm transform to report the EC50 and its logarithm. Prism assumes that you used base 10 logarithms, ...

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