Can Prism fit pharmacokinetic data?

Prism does not have any built-in features to facilitate analysis of pharmacokinetic (PK) data.

 However, Prism can use nonlinear regression to fit any model to your data. You just need to provide the model -- an equation that defines Y as a function of X (often time) and some parameters, or an equation that defines dY/dX as a function of Y and parameters.  Prism can use global fitting to fit two (or more) data sets at once, sharing some parameters between data sets. 

The online Prism Curve Fitting Guide explains the principles of nonlinear regression and all the details of how to fit curves with Prism. This page is a good starting place.

Note that Prism cannot fit models defined by a set of differential equations, or a compartmental diagram. These kinds of models are used a lot in advanced PK work and you'll need to find a different program to do these kinds of analyses.