How is Prism 5 different than Prism 4?

Prism 5 has been improved in hundreds of ways.

The best way to learn about the changes is to read a short list of highlights, and then try the free demo. You'll discover the new features as you use the program. If you prefer to read a comprehensive list of changes, here are the Prism 5 release notes as a 16 page (1 MB) pdf file,