My Prism Mac graphs look awful when pasted into Apple Keynote.
Copy the graph in Prism and paste into a new file in Photoshop with a transparent background. The default size for this file should automatically match the size of the image on the clipboard. Then save the Photoshop file as native psd file with layers option selected. Finally, switch to Keynote and use the Place command to import the psd file. Now your Prism graph will look great in Keynote.
Also check www.apple.com for updates to Keynote which might fix this problem.