About 179 documents, showing 23 to 32

23

This equation is used when X values are concentrations or doses. Use a related equation when X values are logarithms of concentrations or doses.

https://www.graphpad.com/guides/prism/latest/curve-fitting/

24

The best-fit curve will be identical, but the parameter values will differ. The best fit value of the "EC50" will be very different.

GraphPad FAQs

25

Neubig, personal communication). This term is not very standard, and is a bit misleading as there is nothing absolute about an "absolute EC50". The concept (but ...

GraphPad FAQs

26

EC50 values are blank. This problem can occur when: you create (or save) a file in Prism 5.01 and open the file using Prism 4. It only happens when you fit ...

GraphPad FAQs

27

EC50 is the concentration of agonist that gives a response half way between ... Depending on which units Y is expressed in, and the values of Bottom and Top, the ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

28

The pEC50 is defined as the negative logarithm of the EC50. If the EC50 equals 1 micromolar (10 -6 molar), the log(EC50) is -6 and the pEC50 is 6.

GraphPad FAQs

29

Many log(dose) response curves follow the familiar symmetrical sigmoidal shape. The usual goal is to determine the EC50 of the agonist - the concentration that ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

30

The graph below shows two dose-response curves. The goal of the experiment is to determine the two EC50 values. The EC50 is the concentration (dose) that ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

31

It fits four parameters: the bottom and top plateaus of the curve, the EC50 (or IC50), and the slope factor (Hill slope). This curve is symmetrical around ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

32

The EC50 (or IC50) refer to a concentration of agonist (or antagonist) required to increase (or reduce) the measured response to half - or 50% - of its maximal ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/