About 179 documents, showing 3 to 12

3

EC50Control is the concentration of agonist that gives half maximal response in the absence of modulator. Top and Bottom are plateaus in the units of the Y axis ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

4

You should average the logEC50 values, not the EC50 values. Since the distribution of EC50s is usually not symmetrical, the mean of the EC50s is not a good way ...

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5

The usual cause for this problem is misunderstanding the definitions of an EC50. The EC50 is the dose of a drug that provokes a response half-way between ...

GraphPad FAQs

6

The 95% confidence interval of the EC50 is not symmetrical. Sample data. Asymmetrical confidence intervals. The sample data above were fit to the model: ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

7

The potency of a drug is commonly quantified as the EC50, the concentration that leads to 50% maximal response (or the logarithm of the EC50).

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8

The best-fit value for the change in EC50s (the DeltaLogEC50) is 1.50 with a 95% confidence interval ranging from 1.28 to 1.64.

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9

The EC50 is defined quite simply as the concentration of agonist that provokes a response halfway between the baseline (Bottom) and maximum response (Top).

https://www.graphpad.com/guides/prism/latest/curve-fitting/

10

IC50 and EC50 are, respectively, the inhibition and effective concentrations that produce 50% of maximal response from a drug or treatment dose.

GraphPad FAQs

11

EC50 and LogEC50: EC50 is the concentration of agonist that gives half maximal response in the absence of inhibitor. The logEC50 is in the same units you used ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

12

If, as is typical, your doses are equally spaced on a LOG scale, then the uncertainty of the IC50 (or EC50) is symmetrical on a LOG scale. In this case, the SE ...

GraphPad FAQs