Search Results

EC50 is the concentration of agonist that gives a response half way between ... Depending on which units Y is expressed in, and the values of Bottom and Top, the ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Many log(dose) response curves follow the familiar symmetrical sigmoidal shape. The usual goal is to determine the EC50 of the agonist - the concentration that ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

EC50 and LogEC50: EC50 is the concentration of agonist that gives half maximal response in the absence of inhibitor. The logEC50 is in the same units you used ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

It fits four parameters: the bottom and top plateaus of the curve, the EC50 (or IC50), and the slope factor (Hill slope). This curve is symmetrical around ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

First let's look at the variables without a log transform, H + and EC50. Both come pretty close to the definition of a ratio variable.

GraphPad FAQs

EC50 is the concentration of agonist that gives a response half way between ... Depending on which units Y is expressed in, and the values of Bottom and Top, the ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

The EC50, fit by standard dose-response models, is determined by two properties of the agonist: •How well it binds to the receptor, quantified by the ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

The graph below shows two dose-response curves. The goal of the experiment is to determine the two EC50 values. The EC50 is the concentration (dose) that ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

The best-fit curve will be identical, but the parameter values will differ. The best fit value of the "EC50" will be very different.

GraphPad FAQs

In this case, use nonlinear regression to quantify the fold shift in the EC50 and its confidence interval, and to compute a P value that tests the null ...

https://www.graphpad.com/guides/prism/latest/statistics/